Characterization of Malignant Lymphoma in Dogs and Use as a Model for the Development of Treatment Strategies

作者: Frederick R. Appelbaum , Paul A. Brown , Theodore C. Graham , Brenda M. Sandmaier , Friedrich W. Schuening

DOI: 10.1007/978-1-4612-3762-4_6

关键词:

摘要: Malignant lymphoma develops spontaneously in dogs with an annual incidence of 24 per 100,000 [1]. Since these are frequently seen by veterinarians they can, the cooperation veterinarian and owner, be referred for study providing a unique model occurring out-bred species. We others have carried out series studies which disease has been characterized pathologically immunologically shown to resemble human many ways. used this develop methods designed improve broaden application marrow transplantation treatment malignant lymphoma.

参考文章(20)
OW Press, F Appelbaum, JA Ledbetter, PJ Martin, J Zarling, P Kidd, ED Thomas, Monoclonal antibody 1F5 (anti-CD20) serotherapy of human B cell lymphomas Blood. ,vol. 69, pp. 584- 591 ,(1987) , 10.1182/BLOOD.V69.2.584.584
G. H. Theilen, B. R. Madewell, R. E. Weller, C. A. Holmberg, Histologic classification as a prognostic criterion for canine lymphosarcoma. American Journal of Veterinary Research. ,vol. 41, pp. 1310- 1314 ,(1980)
CM Richman, RS Weiner, RA Yankee, Increase in Circulating Stem Cells Following Chemotherapy in Man Blood. ,vol. 47, pp. 1031- 1039 ,(1976) , 10.1182/BLOOD.V47.6.1031.1031
F R Appelbaum, K M Sullivan, C D Buckner, R A Clift, H J Deeg, A Fefer, R Hill, J Mortimer, P E Neiman, J E Sanders, Treatment of malignant lymphoma in 100 patients with chemotherapy, total body irradiation, and marrow transplantation. Journal of Clinical Oncology. ,vol. 5, pp. 1340- 1347 ,(1987) , 10.1200/JCO.1987.5.9.1340
FREDERICK R. APPELBAUM, H. JOACHIM DEEG, RAINER STORB, STEVEN SELF, THEODORE C. GRAHAM, GEORGE E. SALE, PAUL L. WEIDEN, Marrow transplant studies in dogs with malignant lymphoma. Transplantation. ,vol. 39, pp. 499- 504 ,(1985) , 10.1097/00007890-198505000-00008
Frederick R. Appelbaum, H. Joachim Deeg, Rainer Storb, Theodore C. Graham, Keith Charrier, William Bensinger, Cure of malignant lymphoma in dogs with peripheral blood stem cell transplantation. Transplantation. ,vol. 42, pp. 19- 22 ,(1986) , 10.1097/00007890-198607000-00004
E. D. Thomas, R. Leblond, T. Graham, R. Storb, Marrow infusions in dogs given midlethal or lethal irradiation. Radiation Research. ,vol. 41, pp. 113- 124 ,(1970) , 10.2307/3572900
FREDERICK R. APPELBAUM, GEOFFERY P. HERZIG, ROBERT G. GRAW, MALCOLM I. BULL, CHARLES BOWLES, N. CLAUDE GORIN, ALBERT B. DEISSEROTH, Study of cell dose and storage time on engraftment of cryopreserved autologous bone marrow in a canine model. Transplantation. ,vol. 26, pp. 245- 248 ,(1978) , 10.1097/00007890-197810000-00008
Frederick R. Appelbaum, George E. Sale, Rainer Storb, Keith Charrier, H. Joachim Deeg, Ted Graham, Jan C. Wulff, Phenotyping of canine lymphoma with monoclonal antibodies directed at cell surface antigens: Classification, morphology, clinical presentation and response to chemotherapy Hematological Oncology. ,vol. 2, pp. 151- 168 ,(1984) , 10.1002/HON.2900020205