Co-Transcriptional RNA Processing in Plants: Exploring from the Perspective of Polyadenylation

摘要: Most protein-coding genes in eukaryotes possess at least two poly(A) sites, and alternative polyadenylation is considered a contributing factor to transcriptomic proteomic diversity. Following transcription, nascent RNA usually undergoes capping, splicing, cleavage, polyadenylation, resulting mature messenger (mRNA); however, increasing evidence suggests that transcription processing are coupled. Plants, which must produce rapid responses environmental changes because of their limited mobility, exhibit such coupling. In this review, we summarize recent advances our understanding the coupling with plants, describe possible spatial environment important proteins involved. Moreover, how liquid-liquid phase separation, mediated by C-terminal domain polymerase II factors intrinsically disordered regions, enables efficient co-transcriptional mRNA plants.