Phagocytosis of Red Corpuscles

摘要: Savtchenko,1 Levaditi,2 Gruber3 all observed that injection of serum rabbits immunized with guinea-pig blood into the peritoneal cavity guinea-pigs is followed by a marked erythrophagocytosis not only in abdomen, but also blood-making organs, especially spleen, and even circulating (Levaditi). In this phagocytosis take part microcytes as well macrocytes. Ruziczka noted occurrence vitro red corpuscles presence corresponding immune serum.4 This was ascribed Savtchenko to action upon either phagocytes or erythrocytes amboceptor substance sensibilisatrice serum, explanation contested Levaditi Gruber. A year ago Neufeld Topfer5 showed goat contains on after absorption them renders subject guineapig leucocytes vitro. substance, which they designated hemotropic, had no direct leucocytes. Elsewhere6 I have pointed out such substances should be called opsonins (hemopsonins) because their analogy bacteriopsonins Wright Douglas who were first show clearly opsonic function bacteria. Barratt7 found doves hen give strongly for demonstrated this, other cases, acts directly phagocytes. Topfer, Barratt conclude hemotropic substances, hemopsonins, are distinct