Identification and quantitation of 3,4-methylenedioxy-N-methylamphetamine (MDMA, ecstasy) in human urine by 1H NMR spectroscopy. Application to five cases of intoxication
作者： Jonathan Liu , John Decatur , Gloria Proni , Elise Champeil
DOI: 10.1016/J.FORSCIINT.2009.10.022
关键词:
摘要: Identification of 3,4-methylenedioxy-N-methylamphetamine (MDMA, ecstasy) in five cases intoxication using nuclear magnetic resonance (NMR) spectroscopy human urine is reported. A new water suppression technique PURGE (Presaturation Utilizing Relaxation Gradients and Echoes) was used. calibration curve obtained spiked samples. The method gave a linear response (correlation coefficient 0.992) over the range 0.01-1mg/mL. Subsequently, quantitation amount MDMA present samples performed. benefit reliability NMR investigations for with are discussed.
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