An autopsied case of metastatic endocrine carcinoma of the pancreas with primary site difficult to identify

摘要: A 40-year-old man suffering from right cheek swelling was first diagnosed with ameloblastoma or anaplastic poorly-differentiated carcinoma of the head and neck region. He received 2 courses CDDP/TXT chemotherapy (cisplatin 75 mg/m2, docetaxel 80 mg/m2) achieved a partial response, but his pancreas recurred. also response CBDCA/TXL regimen (carboplatin AUC=6, paclitaxel 200 mg/m2), later died progressive disease. The autopsy revealed pathological diagnosis metastatic endocrine pancreas. This case close to cancer an unknown primary (CUP) site, several favorable sub-sets CUP have been identified, which are responsive systemic chemotherapy. Poorly-differentiated neuroendocrine carcinomas like this highly sensitive chemotherapy, careful may clarify its sensitivity prognosis.