Chapter 1 Opiate agonists

摘要: Publisher Summary In this chapter, the use of separation methods for isolation, identification and quantitative analysis natural synthetic opiates is being discussed. The term “opiate” refers specifically to products derived from opium poppy. detection defined may be performed by gas or liquid chromatography, both coupled a mass spectrometer in selected ion monitoring mode, using electron impact chemical ionization. Other modes used with chromatography (nitrogen-selective capture detection) (diode-array detection, electrochemical fluorimetric are still being, continues be, successfully dedicated purposes opiate analysis. To advantages these techniques belong lower cost sometimes very high sensitivity. Because their selectivity, particularly valuable less complicated matrices, like illicit drug specimens pharmaceutical preparations. It also focuses on morphine derivatives semi-synthetic opiates, showing agonistic action at opioid receptors OP1 (δ), OP2 (κ) OP3 (μ). This chapter discusses drugs particular forensic significance upon applications, reported over past decade devoted mainly biological samples.