PET/CT features of lung SABR chest wall toxicity.

作者: Urvashi Singh , Gerard M Walls , Gerard G Hanna , Tom B Lynch , Jonathan McAleese

DOI: 10.1111/1754-9485.13115

关键词:

摘要: Stereotactic ablative radiotherapy offers a radical treatment approach for early stage lung cancers and an aggressive local therapy pulmonary oligometastases from other tumour sites. Chest wall toxicity is one of the key dose-limiting toxicities intrathoracic stereotactic treatments. The description chest using functional imaging has not been reported previously. A 56-year-old male received 60 Gy in 8 fractions delivered by volumetric modulated arc T1bN0M0 clinical left upper lobe cancer. past medical history included poorly controlled type 1 diabetes mellitus, severe peripheral vascular disease obesity. patient attended 9 months later with left-sided, slowly progressive pain. An 18 FDG PET/CT performed order to investigate contralateral lesions revealed FDG-avid focal thickening at superio-lateral thoracic overlying inflammatory stranding keeping indolent process. may present as pain, swelling, fracture skin changes, chjmirocteristics Patients risk factors toxicity, such obesity, smoking should be informed their higher propensity this clinically significant side effect. For patients developing demonstrated case associated findings, anti-inflammatory promptly commenced.

参考文章(5)
L. Yeung, I. Poon, A. Kim, B. Keller, F. Lochray, S. Jain, H. Soliman, P. Cheung, I. Thibault, A. Chiang, D. Erler, Predictors of Chest Wall Toxicity after Lung Stereotactic Ablative Radiotherapy Clinical Oncology. ,vol. 28, pp. 28- 35 ,(2016) , 10.1016/J.CLON.2015.06.009
Atsushi Nambu, Hiroshi Onishi, Shinichi Aoki, Licht Tominaga, Kengo Kuriyama, Masayuki Araya, Ryoh Saito, Yoshiyasu Maehata, Takafumi Komiyama, Kan Marino, Tsuyota Koshiishi, Eiichi Sawada, Tsutomu Araki, Rib fracture after stereotactic radiotherapy for primary lung cancer: prevalence, degree of clinical symptoms, and risk factors BMC Cancer. ,vol. 13, pp. 68- 68 ,(2013) , 10.1186/1471-2407-13-68
Robert W. Mutter, Fan Liu, Andres Abreu, Ellen Yorke, Andrew Jackson, Kenneth E. Rosenzweig, Dose-volume parameters predict for the development of chest wall pain after stereotactic body radiation for lung cancer. International Journal of Radiation Oncology Biology Physics. ,vol. 82, pp. 1783- 1790 ,(2012) , 10.1016/J.IJROBP.2011.03.053
Patrick Murray, Kevin Franks, Gerard G Hanna, A systematic review of outcomes following stereotactic ablative radiotherapy in the treatment of early-stage primary lung cancer. British Journal of Radiology. ,vol. 90, pp. 20160732- 20160732 ,(2017) , 10.1259/BJR.20160732
G.G. Hanna, L. Murray, R. Patel, S. Jain, K.L. Aitken, K.N. Franks, N. van As, A. Tree, P. Hatfield, S. Harrow, F. McDonald, M. Ahmed, F.H. Saran, G.J. Webster, V. Khoo, D. Landau, D.J. Eaton, M.A. Hawkins, UK Consensus on Normal Tissue Dose Constraints for Stereotactic Radiotherapy. Clinical Oncology. ,vol. 30, pp. 5- 14 ,(2018) , 10.1016/J.CLON.2017.09.007