作者: Ingrid Schumann , Ulf Boemer , Ingo Hartung , Karl Heinz Thierauch
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摘要: The invention relates to 3-H-pyrazolopyridines according the general formula (I) in which A, B, D, E, Ra, R1, R2, R3, R4, R5 and q are as defined claims, salts, N-oxides, solvates prodrugs thereof, pharmaceutical compositions comprising said 3-H-pyrazolopyridine compounds, methods of preparing 3-H-pyrazolopyridines, intermediate compounds useful methods, uses preparation well for manufacturing a composition treatment diseases dysregulated vascular growth or accompanied with growth, wherein effectively interfere Tie2 signalling.