The Use of Serum Protein Electrophoresis in Clinical Medicine

作者: ROBERT L. WALL

DOI: 10.1001/ARCHINTE.1958.00260210104015

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摘要: Human plasma is a complex solution containing many proteins, probably hundreds, some of which are present only in trace quantities. The distribution these proteins the normal adult shows an amazing degree uniformity. However, disease states considerable variation quantity individual protein components takes place, referred to asdysproteinemia. Less frequently, certain qualitatively abnormal may develop as response disease, and asparaproteins. These variations have intrigued clinicians since early salt fractionation human serum at turn century. In 1921, Howe,1utilizing 21.5% sodium sulfate simple method fractionation, precipitated from was defined "albumin." This "albumin" subtracted total (corrected for nonprotein nitrogen) represented "globulin." two fractions related

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