摘要: An analysis of BRCA1 and BRCA2 mutations in female relatives carriers identified among 1008 breast cancer patients has provided revised estimates for the risk associated with these mutations. In a Perspective, [Levy-Lahad Plon][1] discuss reported by New York Breast Cancer Study ([ King et al ][2].) what they reveal about influence nongenetic factors on susceptibility. [1]: http://www.sciencemag.org/cgi/content/full/302/5645/574 [2]: http://www.sciencemag.org/cgi/content/short/302/5645/643
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unirioja.es参考文章(10)
Timothy R Rebbeck, Henry T Lynch, Susan L Neuhausen, Steven A Narod, Laura Van't Veer, Judy E Garber, Gareth Evans, Claudine Isaacs, Mary B Daly, Ellen Matloff, Olufunmilayo I Olopade, Barbara L Weber, None, Prophylactic Oophorectomy in Carriers of BRCA1 or BRCA2 Mutations The New England Journal of Medicine. ,vol. 346, pp. 1616- 1622 ,(2002) , 10.1056/NEJMOA012158
Noah D. Kauff, Jaya M. Satagopan, Mark E. Robson, Lauren Scheuer, Martee Hensley, Clifford A. Hudis, Nathan A. Ellis, Jeff Boyd, Patrick I. Borgen, Richard R. Barakat, Larry Norton, Mercedes Castiel, Khedoudja Nafa, Kenneth Offit, Risk-reducing salpingo-oophorectomy in women with a BRCA1 or BRCA2 mutation. The New England Journal of Medicine. ,vol. 346, pp. 1609- 1615 ,(2002) , 10.1056/NEJMOA020119
Muin J. Khoury, Linda L. McCabe, Edward R.B. McCabe, Population Screening in the Age of Genomic Medicine The New England Journal of Medicine. ,vol. 348, pp. 50- 58 ,(2003) , 10.1056/NEJMRA013182
Ann S. Hamilton, Thomas M. Mack, Puberty and genetic susceptibility to breast cancer in a case-control study in twins. The New England Journal of Medicine. ,vol. 348, pp. 2313- 2322 ,(2003) , 10.1056/NEJMOA021293
Mandell JB King MC1, Marks JH, New York Breast Cancer Study Group., None, Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2. Science. ,vol. 302, pp. 643- 646 ,(2003) , 10.1126/SCIENCE.1088759
Virginie Scotet, Marie-Christine Mérour, Anne-Yvonne Mercier, Brigitte Chanu, Thérèse Le Faou, Odile Raguénes, Gérald Le Gac, Catherine Mura, Jean-Baptiste Nousbaum, Claude Férec, Hereditary Hemochromatosis: Effect of Excessive Alcohol Consumption on Disease Expression in Patients Homozygous for the C282Y Mutation American Journal of Epidemiology. ,vol. 158, pp. 129- 134 ,(2003) , 10.1093/AJE/KWG123
Deborah Ford, DF Easton, M Stratton, S Narod, D Goldgar, P Devilee, DT Bishop, B Weber, G Lenoir, J Chang-Claude, H Sobol, M Dawn Teare, J Struewing, A Arason, S Scherneck, J Peto, TR Rebbeck, P Tonin, S Neuhausen, R Barkardottir, J Eyfjord, H Lynch, BAJ Ponder, SA Gayther, JM Birch, A Lindblom, D Stoppa-Lyonnet, Y Bignon, A Borg, U Hamann, N Haites, RJ Scott, CM, and Maugard, H Vasen, S Seitz, LA Cannon-Albright, A Schofield, M Zelada-Hedman, Genetic Heterogeneity and Penetrance Analysis of the BRCA1 and BRCA2 Genes in Breast Cancer Families American Journal of Human Genetics. ,vol. 62, pp. 676- 689 ,(1998) , 10.1086/301749
A. Antoniou, P.D.P. Pharoah, S. Narod, H.A. Risch, J.E. Eyfjord, J.L. Hopper, N. Loman, H. Olsson, O. Johannsson, Å. Borg, B. Pasini, P. Radice, S. Manoukian, D.M. Eccles, N. Tang, E. Olah, H. Anton-Culver, E. Warner, J. Lubinski, J. Gronwald, B. Gorski, H. Tulinius, S. Thorlacius, H. Eerola, H. Nevanlinna, K. Syrjäkoski, O.-P. Kallioniemi, D. Thompson, C. Evans, J. Peto, F. Lalloo, D.G. Evans, D.F. Easton, Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case series unselected for family history: a combined analysis of 22 studies American Journal of Human Genetics. ,vol. 72, pp. 1117- 1130 ,(2003) , 10.1086/375033
Kristin Astrom, Joel E. Cohen, Joan E. Willett-Brozick, Christopher E. Aston, Bora E. Baysal, Altitude is a phenotypic modifier in hereditary paraganglioma type 1: evidence for an oxygen-sensing defect Human Genetics. ,vol. 113, pp. 228- 237 ,(2003) , 10.1007/S00439-003-0969-6
C. B. Begg, On the Use of Familial Aggregation in Population-Based Case Probands for Calculating Penetrance Journal of the National Cancer Institute. ,vol. 94, pp. 1221- 1226 ,(2002) , 10.1093/JNCI/94.16.1221