Lipid–Drug Conjugate for Enhancing Drug Delivery

作者: Danielle Irby , Chengan Du , Feng Li

DOI: 10.1021/ACS.MOLPHARMACEUT.6B01027

关键词:

摘要: … For example, a bromide next to the ester bond facilitates the … for phosphorothioate backbone. (b) Chemical structure of different lipids used for synthesizing lipid conjugated siRNAs. (c) …

参考文章(138)
Hafiz Muhammad Ali, Andrei Maksimenko, Giorgia Urbinati, Hubert Chapuis, Mouna Raouane, Didier Desmaële, Hayashi Yasuhiro, Hideyoshi Harashima, Patrick Couvreur, Liliane Massaad-Massade, Effects of silencing the RET/PTC1 oncogene in papillary thyroid carcinoma by siRNA-squalene nanoparticles with and without fusogenic companion GALA-cholesterol. Thyroid. ,vol. 24, pp. 327- 338 ,(2014) , 10.1089/THY.2012.0544
Elise Lepeltier, Claudie Bourgaux, Heinz Amenitsch, Véronique Rosilio, Sinda Lepetre-Mouelhi, Fatima Zouhiri, Didier Desmaële, Patrick Couvreur, Influence of the nanoprecipitation conditions on the supramolecular structure of squalenoyled nanoparticles. European Journal of Pharmaceutics and Biopharmaceutics. ,vol. 96, pp. 89- 95 ,(2015) , 10.1016/J.EJPB.2015.07.004
Saijie Zhu, Xinran Li, Dharmika S. P. Lansakara-P., Amit Kumar, Zhengrong Cui, A nanoparticle depot formulation of 4-(N)-stearoyl gemcitabine shows a strong anti-tumour activity. Journal of Pharmacy and Pharmacology. ,vol. 65, pp. 236- 242 ,(2012) , 10.1111/J.2042-7158.2012.01599.X
Madhavi C. Chander, Susan Band Horwitz, Prabu Devanesan, Forrest H. Anthony, Sharyn D. Baker, Nigel L. Webb, Philip A. Witman, Lifeng He, Matthews O. Bradley, S. Hemamalini, Charles S. Swindell, Tumor Targeting by Covalent Conjugation of a Natural Fatty Acid to Paclitaxel Clinical Cancer Research. ,vol. 7, pp. 3229- 3238 ,(2001)
Tristan Gollnest, Thiago Dinis de Oliveira, Dominique Schols, Jan Balzarini, Chris Meier, Lipophilic prodrugs of nucleoside triphosphates as biochemical probes and potential antivirals Nature Communications. ,vol. 6, pp. 8716- 8716 ,(2015) , 10.1038/NCOMMS9716
Samantha M. Sarett, Kameron V. Kilchrist, Martina Miteva, Craig L. Duvall, Conjugation of palmitic acid improves potency and longevity of siRNA delivered via endosomolytic polymer nanoparticles Journal of Biomedical Materials Research Part A. ,vol. 103, pp. 3107- 3116 ,(2015) , 10.1002/JBM.A.35413
Sifei Han, Luojuan Hu, Tim Quach, Jamie S. Simpson, Natalie L. Trevaskis, Christopher J. H. Porter, Profiling the Role of Deacylation-Reacylation in the Lymphatic Transport of a Triglyceride-Mimetic Prodrug Pharmaceutical Research. ,vol. 32, pp. 1830- 1844 ,(2015) , 10.1007/S11095-014-1579-9
Lan Feng, Soumya R. Benhabbour, Russell J. Mumper, Oil-filled lipid nanoparticles containing 2'-(2-bromohexadecanoyl)-docetaxel for the treatment of breast cancer. Advanced Healthcare Materials. ,vol. 2, pp. 1451- 1457 ,(2013) , 10.1002/ADHM.201300017
Kavita Yadav, Priyanshu Bhargava, Sandhya Bansal, Manish Singh, Siddhi Gupta, Geeta Sandhu, Sandeep Kumar, Vedagopuram Sreekanth, Avinash Bajaj, None, Nature of the charged head group dictates the anticancer potential of lithocholic acid-tamoxifen conjugates for breast cancer therapy MedChemComm. ,vol. 6, pp. 778- 787 ,(2015) , 10.1039/C4MD00289J
L. Harivardhan Reddy, Jack-Michel Renoir, Veronique Marsaud, Sinda Lepetre-Mouelhi, Didier Desmaële, Patrick Couvreur, Anticancer efficacy of squalenoyl gemcitabine nanomedicine on 60 human tumor cell panel and on experimental tumor. Molecular Pharmaceutics. ,vol. 6, pp. 1526- 1535 ,(2009) , 10.1021/MP900099E