SRSF protein kinase 1 modulates RAN translation and suppresses CGG repeat toxicity

作者: Indranil Malik , Yi‐Ju Tseng , Shannon E Wright , Kristina Zheng , Prithika Ramaiyer

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摘要: Transcribed CGG repeat expansions cause neurodegeneration in Fragile X‐associated tremor/ataxia syndrome (FXTAS). CGG repeat RNAs sequester RNA‐binding proteins (RBPs) …

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