Immune regulation by fungal strain diversity in inflammatory bowel disease

摘要: The fungal microbiota (mycobiota) is an integral part of the complex multikingdom microbial community colonizing the mammalian gastrointestinal tract and has an important role in immune regulation–. Although aberrant changes in the mycobiota have been linked to several diseases, including inflammatory bowel disease–, it is currently unknown whether fungal species captured by deep sequencing represent living organisms and whether specific fungi have functional consequences for disease development in affected …