Single-cell analyses reveal increasing intratumoral heterogeneity as an essential component of treatment resistance in small cell lung cancer

作者: C Allison Stewart , Carl M Gay , Yuanxin Xi , Junya Fujimoto , Neda Kalhor

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摘要: … analyses of CDX models and patient CTCs over the course of therapy. Within each CDX model, … We independently found ITH of protein expression (eg, SLFN11, EZH2, EMT) in CTCs …

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