Small molecule inhibition of ATM kinase increases CRISPR-Cas9 1-bp insertion frequency

作者: Heysol C Bermudez-Cabrera , Sannie Culbertson , Sammy Barkal , Benjamin Holmes , Max W Shen

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摘要: Mutational outcomes following CRISPR-Cas9-nuclease cutting in mammalian cells have recently been shown to be predictable and, in certain cases, skewed toward single …

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