miRNAs as potential diagnostic biomarkers and pharmacogenomic indicators in psychiatric disorders

作者: Evangelia Eirini Tsermpini , Christina I Kalogirou , George C Kyriakopoulos , George P Patrinos , Constantinos Stathopoulos

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摘要: The heterogeneity of psychiatric disorders and the lack of reliable biomarkers for prediction and treatments follow-up pose difficulties towards recognition and understanding of the molecular basis of psychiatric diseases. However, several studies based on NGS approaches have shown that miRNAs could regulate gene expression during onset and disease progression and could serve as potential diagnostic and pharmacogenomics biomarkers during treatment. We provide herein a detailed overview of circulating miRNAs …

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