Identification of risk genes for Alzheimer’s disease by gene embedding

作者: Yashwanth Lagisetty , Thomas Bourquard , Ismael Al-Ramahi , Carl Grant Mangleburg , Samantha Mota

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摘要: Most disease-gene association methods do not account for gene-gene interactions, even though these play a crucial role in complex, polygenic diseases like Alzheimer's disease …

参考文章(1)
Panagiotis Katsonis, Olivier Lichtarge, Christie Buchovecky, Amanda Koire, Stephen J. Wilson, Young Won Kim, A method to delineate de novo missense variants across pathways prioritizes genes linked to autism. Science Translational Medicine. ,vol. 13, ,(2021) , 10.1126/SCITRANSLMED.ABC1739