Selection analysis identifies clusters of unusual mutational changes in Omicron lineage BA. 1 that likely impact Spike function
作者： Darren P Martin , Spyros Lytras , Alexander G Lucaci , Wolfgang Maier , Björn Grüning
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摘要: Among the 30 nonsynonymous nucleotide substitutions in the Omicron S-gene are 13 that have only rarely been seen in other SARS-CoV-2 sequences. These mutations cluster within …
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Vincent A. Voelz, John D. Chodera, Neha Vithani, Elisa Fadda, Gregory R. Bowman, Rafal P. Wiewiora, Rafal P. Wiewiora, Sukrit Singh, Maxwell I. Zimmerman, Aoife M Harbison, Justin R. Porter, Matthew F. D. Hurley, Jonathan H. Borowsky, Artur Meller, Upasana L. Mallimadugula, Carl A Fogarty, Michael D. Ward, Joseph E. Coffland, Catherine E. Kuhn, SARS-CoV-2 Simulations Go Exascale to Capture Spike Opening and Reveal Cryptic Pockets Across the Proteome bioRxiv. ,(2020) , 10.1101/2020.06.27.175430