Large library docking for novel SARS-CoV-2 main protease non-covalent and covalent inhibitors

作者: Elissa A Fink , Conner Bardine , Stefan Gahbauer , Isha Singh , Tyler C Detomasi

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摘要: … Among them is the orally active MPro 67 inhibitor S-2176227, which has entered clinical trials. … aggregation than 0.01% Triton-X 100, we deemed the weak aggregation of these 171 …

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