Gene Ontology Development and Implementation at the Saccharomyces Genome Database

摘要: The Saccharomyces Genome Database (SGD; http://genome-www. stanford. edu/Saccharomyces) is a model organism database that provides information about the genes and proteins of the budding yeast S. cerevisiae and develops resources that allow the scientific community to analyze and retrieve this information. SGD uses the controlled vocabulary terms of the Gene Ontology (GO) to describe the molecular function, biological process, and cellular component of a gene product. The GO terms have a specific relationship to each other that is determined by a parent/child structure. SGD has developed resources that use this structure to identify shared parent terms for a group of gene products. The GO Term Finder (http://genome-www4. stanford. edu/cgi-bin/SGD/GO/goTermFinder) and the GO Term Mapper (http://genome-www4. stanford. edu/cgi-bin/SGD/GO/goTermMapper) find common function, process, or cellular localization terms for a sct of genes while the Feature Search (http://genome-www4. stanford, edu/cgi-bin/SGD/search/featureSearch) retrieves gene products that have a similar function, process, or localization.