Treatment of cancer with dual targeting of cd47 and egfr

作者: Irving L Weissman , Kelly Marie MCKENNA , Stephen WILLINGHAM , Doris Po Yi HO , Piero D Dalerba

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摘要: UCSJYZPVAKXKNQ-HZYVHMACSA-N 1-[(1S, 2R, 3R, 4S, 5R, 6R)-3-carbamimidamido-6-{[(2R, 3R, 4R, 5S)-3-{[(2S, 3S, 4S, 5R, 6S)-4, 5-dihydroxy-6-(hydroxymethyl)-3-(methylamino) oxan-2-yl] oxy}-4-formyl-4-hydroxy-5-methyloxolan-2-yl] oxy}-2, 4, 5-trihydroxycyclohexyl] guanidine Chemical compound CN [C@ H] 1 [C@ H](O)[C@@ H](O)[C@ H](CO) O [C@ H] 1O [C@@ H] 1 [C@](C= O)(O)[C@ H](C) O [C@ H] 1O [C@@ H] 1 [C@@ H](NC (N)= N)[C@ H](O)[C@@ H](NC (N)= N)[C@ H](O)[C@ H] 1O UCSJYZPVAKXKNQ-HZYVHMACSA-N 0.000 description 4RZCIEJXAILMSQK-JXOAFFINSA-N 5-Methyluridine triphosphate Chemical compound O= C1NC (= O) C (C)= CN1 [C@ H] 1 [C@ H](O)[C@ H](O)[C@@ H](COP (O)(= O) OP (O)(= O) OP (O)(O)= O) O1 RZCIEJXAILMSQK-JXOAFFINSA-N 0.000 description 4

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