Biomarker strategy for a phase 1 study of ORIC-944, a potent and selective allosteric PRC2 inhibitor, in patients with metastatic prostate cancer

作者: Anneleen Daemen , Natalie Yuen , Aleksandr Pankov , Eric A Ariazi , Subhash D Katewa

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摘要: Background1. ORIC-944 Induced Dose-dependent H3K27me3 Reduction in Murine Skin Punch Biopsies In Vivo

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