Combined Model of OCT Angiography and Structural OCT Parameters to Predict Paracentral Visual Field Loss in Primary Open-Angle Glaucoma

摘要: PurposeTo assess a model combining OCT angiography (OCTA) and OCT parameters to predict the severity of paracentral visual field (VF) loss in primary open-angle glaucoma (POAG).DesignCross-sectional study.ParticipantsForty-four patients with POAG and 42 control subjects underwent OCTA and OCT imaging with a swept-source OCT device.MethodsThe circumpapillary microvasculature was quantified for vessel density (cpVD) and flow (cpFlow) after delineation of Bruch’s membrane opening and removal of large vessels. Retinal nerve fiber layer thickness (RNFLT) and Bruch’s membrane opening–minimum rim width (BMO-MRW) were measured from structural OCT. Paracentral total deviation (PaTD) was defined as the average of the total deviation values within the central 10 degrees on Humphrey VF testing (24-2) for upper and lower hemifields. The OCT and OCTA parameters were measured in the …