1742P Gender differences in incidence trends of early-onset GI cancer: The European perspective

摘要: BackgroundThe US Surveillance, Epidemiology and End Result (SEER) data indicate an increasing incidence of early-onset cancer across the GI tract. A female predominance has been shown for early-onset pancreatic cancer (EOPC) in the US. Due to environmental factors which may underlie the pathogenesis of early-onset cancer, incidence across the globe may differ. However, data regarding the incidence of gastrointestinal cancers in young patients in Europe is scarce. Therefore, we aimed to investigate patterns of GI cancers in young patients across various European countries.MethodsNational cancer registries of seven European countries-Germany, Netherlands, Spain, Slovenia, Norway, Czech Republic and Israel-were approached for absolute number of cancer incidences per age group (15-50 years in 5-year intervals) and the size of the population for each age group yearly from 2008-2018. Data was …