Conception by fertility treatment and cardiometabolic risk in middle childhood

摘要: ObjectiveTo evaluate whether children conceived using assisted reproductive technology (ART) or ovulation induction (OI) have greater cardiometabolic risk than children conceived without treatment.DesignClinical assessments in 2018–2019 in the Upstate KIDS cohort.SettingClinical sites in New York.Patient(s)Three hundred thirty-three singletons and 226 twins from 448 families.Intervention(s)Mothers reported their use of fertility treatment and its specific type at baseline and approximately 4 months after delivery. High validity of the self-reported use of ART was previously confirmed. The children were followed up from infancy through 8–10 years of age. A subgroup was invited to participate in clinic visits.Main Outcome Measure(s)The measurements of blood pressure (BP), arterial stiffness using pulse wave velocity, anthropometric measures, and body fat using bioelectrical impedance analysis were performed …