Quantitative Comparison Of Acinar Airspaces In Inbred Mouse Strains Using MicroCT Imaging

摘要: Introduction therapy. It is therefore important to investigate the phenotypic differences in these common research strains in order to account for strain variations in lung structure and better understand changes associated with disease. Previous studies have looked at characterizing the upper airway through various imaging techniques. We seek to extend this phenotype characterization to look at structural variations in acinar airspaces through the use of Ultra High-Resolution microCT imaging.: Six mice each from two common research strains (C57B6, A/J) are scanned at multiple in-vivo volumes, fixed at 20cm HO using