Article type: Full Paper

摘要: Purpose Brain imaging exams typically take 10-20 minutes and involve multiple sequential acquisitions. A low-distortion whole-brain EPI-based approach was developed to efficiently encode multiple contrasts in one acquisition, allowing for calculation of quantitative parameter maps and synthetic contrast-weighted images.Methods Inversion prepared spin-and gradient-echo EPI was developed with slice-order shuffling across measurements for efficient acquisition with T1, T2, and T2* weighting. A dictionary-matching approach was used to fit the images to quantitative parameter maps, which in turn were used to create synthetic weighted images with typical clinical contrasts.