作者: L Liu , A Gurevich , P Noël , M Itkin
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摘要: PurposeCT lymphangiography is a novel imaging method and crucial for diagnosis of the lymphatic diseases. Spectral CT can provide superior imaging of central lymphatic structures by separating and quantifying iodinated contrast agents compared to MR lymphangiography. We evaluate the feasibility of in vivo lymphatic system imaging using spectral CT.Materials and MethodsBilateral superficial inguinal lymph nodes of a Yorkshire pig were injected at 0.1 mL/s with 20 mL of iodinated contrast agent (Isovue-300, Bracco Diagnostics). The pig was simultaneously scanned with a second-generation dual-layer spectral CT (Spectral CT 7500, Philips Healthcare) at a tube voltage of 140 kVp and an exposure of 300 mAs approximately every 45 s for 12 minutes. Both conventional images and iodine density maps were reconstructed at a slice thickness of 0.67 mm and a field of view of 350 mm, and respective contrast to …