561: Biofilm phenotyping of patients chronically infected with Pseudomonas aeruginosa reveals a novel, putative biomarker for biofilm infection in cystic fibrosis

摘要: 561 Biofilm phenotyping of patients chronically infected with Pseudomonas aeruginosa reveals a novel, putative biomarker for biofilm infection in cystic fibrosis D. Power1, O. Soren1, T. Garfield2, P. Skipp3, S. Faust4, G. Connett5, J. Webb1. 1Institute for Life Sciences, University of Southampton, Southampton, UK; 2Faculty of Medicine, University of Southampton, Southampton, UK; 3Centre for Proteomics Research, University of Southampton, Southampton, UK; 4Faculty of Medicine, Clinical and Experimental Sciences, University of Southampton, Southampton, UK; 5Paediatrics, University Hospital Southampton NHS Foundation Trust, Southampton, UK Background: Colonization of Pseudomonas aeruginosa in the airways is associatedwith persistentmorbidity and greatermortality in cystic fibrosis (CF) patients. Current CF treatment strategies include aggressive antibiotic regimes aimed at eradicating or controlling …