O-6-D05/1293/Comparison of Visual Analogue Scale and Time Trade-Off Valuations of Pediatric Health States

摘要: Aims The validity of the HUI-3 and the SF-6D was determined in a sample of patients with latent and active tuberculosis (TB). We hypothesized that (1) latent patients would have higher scores than those with active TB,(2) patients with recent adverse drug reactions (ADRs) to TB drugs would have lower scores and (3) that agreement between the measures would be low. Methods Patients attending an urban clinic with recently diagnosed latent or active TB (n= 200) were given a selfadministered questionnaire that included the HUI-3, SF-6D, sociodemographics, and a drug toxicity index. Agreement between the utility instruments was assessed using the Intraclass Correlation Coefficient (ICC) with a 2-way mixed effect model (random subject effects and fixed instrument effects). Results 170 respondents (96 female) completed the survey (85% response); 101 latent and 69 active TB patients. 40% of latent and 61% of …