摘要: Tumors of the pancreas present a variety of challenges to surgical pathologists. The most common type of pancreatic neoplasm, invasive ductal adenocarcinoma, is notoriously difficult to diagnose because of overlapping features with chronic pancreatitis. Furthermore, the relative inaccessibility of the pancreas implies that the diagnosis of this usually fatal tumor type is often established on the basis of only a minimal amount of pathologic material. Also challenging is accurate classification of other types of tumors of the pancreas, many of which are less aggressive than ductal adenocarcinoma. However, recent work has helped clarify the diagnostic features of cystic and intraductal neoplasms, endocrine neoplasms, acinar cell neoplasms, and related entities, as well as rare variants of ductal adenocarcinoma. In fact, accurate diagnosis is now usually possible, particularly when ancillary diagnostic and radiographic …