Intermittent Fasting against Cancer Development and Progression: Highlighting Potential Anticancer Molecular Mechanisms

摘要: Background Intermittent fasting (IF) diets have been popular since the last few decades because of their provable clinical efficiency on weight control of the subjects. These diet types are generally safe, resulting in health promoting effects against several human diseases like cardiovascular diseases, diabetes mellitus, neurogenerative disorders and cancer. Objective To review whether IF can act against cancer development and progression, highlighting potential anticancer molecular mechanisms in clinical studies. Methods Applied summarization of the available clinical studies investigating the effectiveness of IF against cancer development and progression and cancer-induced indicators. Scientific databases, e.g., PubMed, and Scopus, were comprehensively searched using relative words to identify in vivo and in vitro data, as well as clinical studies. Results IF seems to exert health-promoting effects in cancer …