Synergistic combinations of pi3k-and mek-inhibitors
作者： Christine Fritsch , Xizhong Huang , Markus Boehm , Emmanuelle DI TOMASO , Jan GCE COSAERT
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摘要: LIRYPHYGHXZJBZ-UHFFFAOYSA-N Trametinib Chemical compound CC (= O) NC1= CC= CC (N2C (N (C3CC3) C (= O) C3= C (NC= 4C (= CC (I)= CC= 4) F) N (C) C (= O) C (C)= C32)= O)= C1 LIRYPHYGHXZJBZ-UHFFFAOYSA-N 0.000 claims description 76ACWZRVQXLIRSDF-UHFFFAOYSA-N 6-(4-bromo-2-fluoroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide Chemical compound OCCONC (= O) C= 1C= C2N (C) C= NC2= C (F) C= 1NC1= CC= C (Br) C= C1F ACWZRVQXLIRSDF-UHFFFAOYSA-N 0.000 claims description 68
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