Chiasmal malformations dataset: a unique neuroimaging testbed

摘要: The human optic chiasm is formed normally by almost equal populations of crossing and non-crossing optic nerve fibers. This proportion can be affected by rare disorders, such as albinism or achiasma (Hoffmann and Dumoulin, 2015), causing, respectively, over-or under-representation of crossing fibers. In the light of recent studies revealing those differences from anatomical measures (Puzniak et al., 2019), the optic chiasm appears as a valuable model for researchers interested in the impacts of deficits of vision on brain white matter or tractography methods developments. In order to provide the research community with an access to this unique model, we make the MRI dataset, thoroughly describing chiasmal malformations, available. We recruited patients with albinism (n= 9), achiasma (n= 2), and matching controls (n= 8). For the patients we collected ophthalmological records including visual acuity, fixation …