S4‐01‐03: Neurobiologic features of cognitive superaging

摘要: BackgroundThe Northwestern SuperAging study demonstrates that it is possible for individuals over age 80 to have memory performance at least as good as individuals in their 50s and 60s, dispelling the notion that lower test performance over age 80 is an unavoidable consequence of aging.MethodsInitial results suggest SuperAgers have distinct neurobiologic features from those of cognitively average octo-and nonagenarians, including lack of “typical” age-associated cortical atrophy and an unexpected finding of increased thickness of the anterior cingulate cortex.Results