P27 Bacterial coinfection and antibiotic stewardship in patients with COVID-19: a systematic review and meta-analysis

摘要: Introduction Understanding the proportion of patients with COVID-19 who have respiratory bacterial coinfections and the responsible pathogens is important to managing COVID-19 effectively while ensuring responsible antibiotic use. Objectives To estimate the frequency of bacterial coinfection in COVID-19 patients and of antibiotic prescribing and to appraise the use of antibiotic stewardship criteria. Methods Systematic review and meta-analysis was performed using major databases up to May 15, 2020. We included studies that reported a) proportion/prevalence of bacterial coinfection in COVID-19 patients and b) use of antibiotics. Where available, data on duration and type of antibiotics, adverse events, and any information about antibiotic stewardship policies were also collected. Results We included 39 studies with a total of 10 …