Assessing risk of death in patients with CAP: A 2-step approach.(Clinical Consultation).

作者: Drahomir A Aujesky , Michael J Fine

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摘要: * The average mortality rate associated with CAP ranges from 5.1% for hospitalized and ambulatory patients to 36.5% for patients admitted to the ICU.'Individual clinical risk factors that are independently associated with short-term mortality in patients with CAP include demographic factors (for example, age), comorbid conditions (for example, heart disease, chronic renal disease, and cancer), symptoms and signs (for example, vital sign alterations), and laboratory and radiographic findings (for example, hypoxemia, elevated serum urea nitrogen level, and pleural effusion).(2)However, these risk factors are associated with only moderate increases in the risk of death, with odds ratios usually ranging from 1.2 to 5.4.(2) Therefore, combinations of individual predictors are necessary to accurately assess short-term risk of death and guide initial management decisions, such as whether a patient is treated as an outpatient …

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