Magnetoelastic microcarriers and monitoring system

摘要: Cell therapies can improve the prognosis of many once untreatable diseases. Although many research projects, clinical trials, and business activities have been pursued for cell therapies, there are significant challenges to consistently and effectively assess cell number/volume and cell quality/microenvironment during the cell manufacturing process. In particular, existing technology for the tracking of cell number and monitoring of local microenvironments of the cells in a bioreactor often lead to the destruction of cells and increase the chances of contamination for a batch. Thus, there is a need for improved apparatus, systems, and methods that allow for non-intrusive and continuous monitoring of cell growth in a bioreactor.