Melatonin and clock genes expression in the cardiovascular system

摘要: Introduction 3. Circadian oscillations and clock genes 4. Melatonin and the circadian system 4.1. Melatonin and clock genes in the central oscillator 4.2. The effect of melatonin on the peripheral oscillators 4.2. 1. Cardiovascular system 5. Disturbances of circadian rhythms in the cardiovascular system 5.1. Non-dipping blood pressure profile 5.2. Mechanisms underlying non-dipping BP rhythmicity 5.2. 1. Renin-angiotensin-aldosterone system and sympathetic system 5.2. 2. Circadian system, clock genes and melatonin 6. Summary and perspective 7. Acknowledgement 8. References