HPV detection at menopause

摘要: A cohort of 843 women aged 35 to 60 years were followed for 2 years in this study of age-specific human papillomavirus (HPV) prevalence, which has a bimodal incidence in many populations, perhaps as a result of cohort effects, new sex partnerships, or HPV reactivation. Researchers were evaluating the reasons for the lack of a second peak in the United States.Gravitt and colleagues stratified women according to low risk of prior infection (< 5 selfreported lifetime sex partners) and higher risk (≥ 5 self-reported lifetime sex partners). The age-specific prevalence of 14 high-risk HPV genotypes declined with age among low-risk women but not among high-risk women. The population attributable risk for HPV due to greater than five lifetime sex partners was higher among older women (87.2%) than younger women (28.0%). The population attributable risk for a new sex partner was 28% among women 35 to 49 years and 7.7% in women aged 50 to 60 years.