作者: Diederik Esser , James I Dower , Juri C Matualatupauw , Marianne Geleijnse , Daan Kromhout
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摘要: BackgroundThere is increasing evidence that consumption of cocoa products have a beneficial effect on cardiometabolic health, but the underlying mechanisms remain unclear. Cocoa contains a complex mixture of flavan-3-ols. Epicatechin, a major monomeric flavan-3-ol, is considered to contribute to the cardioprotective effects of cocoa. We investigated the effects of pure epicatechin supplementation on whole genome gene expression profiles of circulating immune cells.