作者: B Nelson , J Johnson , D Koch , Q Smith , B Gadomski
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摘要: Materials and Methods: Twelve hindlimbs were acquired from skeletally mature ewes. Treatment groups include an 8 mm diameter ILN (ILN-8), 10 mm ILN (ILN-10), and 4.5 mm broad LCP and intact (control) tibia (n= 3/group). A mid tibia 5 cm osteotomy was created (except in controls). A custom guide maintained the defect size during implantation. Non-destructive mechanical testing of constructs was performed in axial compression, four-point bending and torsion. Stiffness was calculated from the load-displacement curve. Statistical comparisons were made between groups.Results: Axial rigidity of ILN-8 (6% decrease) and ILN-10 (10% increase) most closely replicated intact tibias. The LCP was 53% lower than intact. Bending rigidity of ILN-10 most closely matched the intact (18% decrease). ILN-8 bending rigidity was 55% lower and LCP was 43% higher than intact. Torsional rigidity of ILN-10 most closely …