TCT-214 Right Ventricular Function in Patients Undergoing Impella-Assisted High-Risk Percutaneous Coronary Intervention: Insights From the cVAD PROTECT III Study

摘要: BackgroundRight ventricular dysfunction (RVD) is an important prognostic factor in several cardiac conditions. However, the impact of RVD on the clinical outcome of patients undergoing Impella-assisted high-risk percutaneous coronary intervention is unknown.MethodsPatients from the prospective, multicenter PROTECT III study were stratified according to the presence of RVD, defined as fractional area change< 35%, tricuspid annular plane systolic excursion< 17 mm, or S wave of the lateral tricuspid annulus< 9.5 cm/s. Endpoints were in-hospital outcomes, 90-day major adverse cardiac and cerebrovascular events (death, myocardial infarction, stroke, repeat revascularization), and 1-year mortality.ResultsOf 239 patients who underwent RV function assessment, 124 had RVD. Lower left ventricular ejection fraction, higher blood urea nitrogen levels, and more severe RV dilatation were independently associated …