作者: R Ghorbani , T Mahdavi , E Nasiri , R Gazor , H Moladoust
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摘要: Background Formaldehyde (FA) is a suspected reproductive toxicant, which may cause significant adverse effects on human reproductive system. Given to its widespread use in occupational setting, and more recently, in several industries related to construction and household products, everyone may be exposed to FA. This study was designed to determine the effect of FA and to investigate possible protective role of vitamin E (VE) on male rat reproductive system. Materials and Methods 32 adult male wistar rats were randomly divided into 4 groups:(1) control rats,(2) Rats treated with vehicle (corn-oil),(3) rats treated with FA (FAt), and (4) rats treated with FA plus VE plus vehicle (FAt+ VE) groups. FAt and FAt+ VE groups were exposed to FA by intraperitoneal injection (10 mg/kg/day) for 2 weeks. Furthermore, FAt+ VE group were orally administered VE (30mg/kg/day) simultaneously. After the treatment, serum …