Efficacy and Safety of Lasmiditan for Acute Treatment of Migraine in Adults: A Meta‐Analysis

摘要: Monotherapy with triptans in acute migraine is ineffective in many patients and contraindicated in certain cardiovascular diseases where alternative therapeutic options are necessary to explore. This meta‐analysis has evaluated the efficacy and safety of lasmiditan for the treatment of acute migraine in adults. After performing a literature search on MEDLINE/PubMed, Scopus, Cochrane databases, and International Clinical Trial Registry Platform, reviewers assessed eligibility and extracted data from 4 relevant articles. Preferred Reporting Items for Systematic Reviews and Meta‐Analysis guidelines were followed in the selection, analysis, and reporting of findings. A random‐effects model was used to estimate effect size. Quality assessment was done using the risk of bias assessment tool and meta‐regression for probable variables affecting effect size. Subgroup analysis was done depending on the dose of …