A. FERRAMOSCA, ME GIULIANI 4, S. GORBI 4, L. GRAUSO 2, MG LIONETTO, L. MAGLIOZZI 3, E. MOLLO 2, L. PITTURA 4, G. POLESE 3, F. REGOLI 4, V. ZARA, A. TERLIZZI

摘要: Results-Fish revealed a high frequency of occurrence of C. racemosa in the stomach contents at invaded areas (72.7 and 85.7%) while the alga was not detected in organisms from control, non-invaded area. We demonstrated that D. sargus accumulates one of the metabolites synthesized by C. racemosa at concentrations ranging from zero to more than one hundred of µg/g, depending on the analyzed tissue, with the highest concentrations found in brain, liver and red muscle. The presence of C. racemosa in the diet of D. sargus, as indicated by the significant accumulation of caulerpin in tissues, caused the onset of various biological effects, including activation of some enzymatic pathways (catalase, glutathione peroxidases, glutathione S-transferases, total glutathione and the total oxyradical scavenging capacity, 7-ethoxy resorufin O-deethylase), the inhibition of others (acetylcholinesterase and acylCoA oxidase), an increase of hepatosomatic index and the decrease of gonadosomatic index (Fig. 1A)(Felline et al., 2012; Gorbi et al., in press). The C. racemosa based-diet has moreover, the potential to induce changes in the nutritional properties of D. sargus. Fish feeding on C. racemosa showed indeed, an altered muscle fatty acids composition, with a lower percentage of polyunsaturated fatty acids (PUFA) of the n-3 and n-6 series, such as eicosapentaenoic (EPA, C20: 5),