A medieval case of Paget's disease of bone with complications

摘要: Gross, radiographic and microscopic study of a skeleton of an elderly male, excavated from a British Mediaeval site, revealed indications of Paget's disease of bone. Several fractures are also present and represent secondary complications. Some joints show unusually severe osteoarthritic changes which may also be secondary to the Pagetic process. Microscopic analysis showed Pagetic changes in part of the skeleton which was grossly and radiographically normal; this serves to emphasise that the true frequency of Pagetic lesions is likely under-estimated both in paleopathological study and in radiographic surveys of living subjects.Introduction.