Early Impairment of Trabecular Microarchitecture Assessed With HR-pQCT in Patients With Stage II-IV Chronic Kidney Disease

摘要: GFR (MDRD), mL/min per 1.73 m2 75 Æ 17 79 Æ 17 ÃÃà 74 Æ 19 ÃÃÃà 33 Æ 12 Ã, Ãà GFR (Cockcroft), mL/min 63 Æ 18 60 Æ 16 ÃÃà 50 Æ 16 ÃÃÃÃà 27 Æ 7 Ã, Ãà Body mass index, kg/m2 28.5 Æ 3.6 26.8 Æ 3.3 ÃÃà 25.2 Æ 3.1 26.7 Æ 4.6 à Age, Years 69 Æ 8.6 70.7 Æ 9 ÃÃà 73.2 Æ 7.8 71.4 Æ 7.6 DXA hip T-score–0.5 Æ 0.7–1.7 Æ 0.4 ÃÃÖ2.7 Æ 0.6—DXA lumbar T-score 0.4 Æ 1.3–1.1 Æ 0.9 ÃÃÖ2 Æ 1.2—Tibial HR-pQCTTotal vBMD, mg HA/cm3 312 Æ 53 271 Æ 46 ÃÃà 231 Æ 50 ÃÃà 288 Æ 58 à Cortical vBMD, mg HA/cm3 851 Æ 55 825 Æ 59 ÃÃà 785 Æ 85 ÃÃÃà 832 Æ 62 Trabecular vBMD, mg HA/cm3 188 Æ 34 159 Æ 30 ÃÃà 134 Æ 34 ÃÃÃà 172 Æ 35 Ã, Ãà Trabecular number, mm À1 1.86 Æ 0.26 1.65 Æ 0.24 ÃÃà 1.41 Æ 0.28 ÃÃÃà 1.75 Æ 0.27 Ã, Ãà Trabecular separation, mm 465 Æ 78 542 Æ 110 ÃÃà 662 Æ 168 ÃÃÃà 503 Æ 94 Ã, Ãà Trabecular distribution, mm 216 Æ 51 267 Æ 125 …