Impact of Age–related Macular Degeneration on Vision–related Quality of Life in Latinos. The Los Angeles Latino Eye Study (LALES)

摘要: Purpose: To assess the impact of early (soft indistinct drusen, retinal pigment abnormalities) and advanced (exudative, geographic atrophy) age–related macular degeneration (AMD) on vision–related quality of life in Latinos. Methods: The LALES is a population–based prevalence study to assess the presence of eye disease and quality of life (QOL) in Latinos (primarily Mexican–American), aged 40 and older. All participants completed a detailed eye examination including stereoscopic fundus photography and a standardized interview including the NEI–VFQ–25. AMD was graded from fundus photographs using standardized protocols. The NEI–VFQ–25 subscale scores were calculated using standard algorithms. The covariate–adjusted mean QOL scores were compared between early and late AMD using analysis of covariance. Covariates included standard sociodemographic factors, comorbidities, visual …