Serological and Molecular Detection of Cardiotropic Viruses in Adults With Myocarditis in Egypt

摘要: Background: Recent studies have shown that several viruses are frequently encountered in myocarditis, with suggestions that multiple viral species play a role in the transition from myocarditis to dilated cardiomyopathy. The purpose of this study was to screen patients with suspected viral myocarditis for anti-viral antibodies by ELISA and viral genomes by using polymerase chain reaction (PCR) to detect the different cardiotropic viruses that may be involved in the pathogenesis of the disease.Methods and Results: This is a prospective observational study. We recruited 51 patients with clinically suspected myocarditis presenting from 1st October 2020 till 31st March 2021. All patients were subjected to full history and examination, ECG, echocardiography, laboratory testing including troponin, cardiac magnetic resonance (CMR) with contrast and coronary angiography. Sera were obtained from all patients for detection …